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Acetaminophen has actually been related to scenarios of acute liver failure, sometimes leading to liver transplant and Dying.

Pores and skin and subcutaneous tissue disorders: allergic reactions for instance pores and skin rashes, urticaria, pruritus, perspiring and facial oedema. Musculoskeletal and connective tissue Diseases: Uncontrolled muscle mass actions. Muscle rigidity might manifest right after high doses.

The presence of other clinical complications might have an effect on the use of this medicine. Make sure you convey to your doctor Should you have some other medical complications, Primarily:

By selecting this button that you are confirming that you're a patient who has long been prescribed a Teva medicine by a United kingdom Health care professional (or their caregiver).

- Sedative antihistamines – Improved sedative and hypotensive impact and enhanced hazard of respiratory melancholy

Opioid analgesics need to be averted in sufferers with biliary tract Conditions or utilized together with an antispasmodic.

Reporting of suspected adverse reactions Reporting suspected adverse reactions following authorisation from the medicinal solution is essential. It permits ongoing monitoring on the benefit/threat balance in the medicinal item.

If you need to choose codeine for various weeks, your treatment method plan could involve particulars of how and when to stop getting this medicine.

Codeine, specifically together with other analgesics which include paracetamol, has actually been shown to generally be powerful in acute nociceptive ache.

Liver condition—Use with warning. The consequences can be improved because of slower elimination of your click here medication from the human body.

Administration to nursing Girls is not encouraged as codeine phosphate could be secreted in breast milk and should bring about respiratory despair from the infant.

The Drug Enforcement Administration classifies codeine and hydrocodone of their pure sorts as Program II medications. This suggests they have a higher likely for misuse and may result in intense Actual physical or psychological dependence.

Discontinuation ought to be completed step by step in individuals who could possibly have produced Bodily dependence, to avoid precipitating withdrawal indicators.

four.6 Pregnancy and lactation Pregnancy Just like all drugs caution must be exercised through pregnancy, especially in the main trimester. A achievable Affiliation with respiratory and cardiac malformations has become reported adhering to to start with trimester more info exposure to codeine.